Rapid Detection of Prothrombotic Mutations of Prothrombin (G20210A), FactorV (G1691A), and Methylenetetrahydrofolate Reductase (C677T) by Real-Time Fluorescence PCR with the LightCycler
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چکیده
منابع مشابه
Rapid detection of prothrombotic mutations of prothrombin (G20210A), factor V (G1691A), and methylenetetrahydrofolate reductase (C677T) by real-time fluorescence PCR with the LightCycler.
storage of blood at room temperature is uncertain, but one possibility is that cleavage of the antigen occurs, releasing smaller fragments, each with multiple OVX1 epitopes. Different cutoffs at 7.2, 10.5, or 12.1 kilounits/L have been used in clinical studies (2, 4). The present findings, therefore, are clinically relevant because the assay range is narrow and the effect we have noted can caus...
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Objectives: To better understand the etiologic factors that can influence preeclampsia, we investigated hereditary factors for thrombosis, FV Leiden, F II 20210A mutation and the polymorphism C677T of the MTHFR, as singly and as in association, in a group of women from Ceará stateNortheast Brazil with severe preeclampsia. Material and Methods: We conducted a case-control study. 101 cases of sev...
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The aim of this study was to investigate the relationship between recurrent miscarriages and factor V Leiden, prothrombin G20210A and C677T methylenetetrahydrofolate reductase (MTHFR) mutations. In this case-control study the prevalence of factor V Leiden, prothrombin G20210A and C677T methylenetetrahydrofolate reductase mutations was determined in a consecutive series of 80 recurrent miscarria...
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according to Chisholm and Mason [5]. A diagnosis of primary Sjögren’s syndrome was made according to the revised European classification criteria for Sjögren’s syndrome [6]. Prednisolone (1mg/kg/day) treatment was started with some improvement in the low back pain. The patient was discharged. Ten days later after his discharge, the patient was referred back to us because of recent onset haemato...
متن کاملPrevalence of Three Prothrombotic Polymorphisms: Factor V G1691A, Factor II G20210A and Methylenetetrahydrofolate Reductase (MTHFR) C 677T in Argentina
ORIGINAL ARTICLE Prevalence of Three Prothrombotic Polymorphisms: Factor V G1691A, Factor II G20210A and Methylenetetrahydrofolate Reductase (MTHFR) C 677T in Argentina Valeria Genoud1, Mercedes Castañon1, Joyce Annichino-Bizzacchi2, Jorge Korin1 and Lucı́a Kordich1 on behalf of the Grupo Cooperativo Argentino de Hemostasia y Trombosis 1Facultad de Ciencias Exactas y Naturales. Dpto. Quı́mica Bio...
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ژورنال
عنوان ژورنال: Clinical Chemistry
سال: 1999
ISSN: 0009-9147,1530-8561
DOI: 10.1093/clinchem/45.5.694